An unexpected giant problem — Giant condyloma (Buschke–Lowenstein tumor)

A 49-year-old man with a long-standing history of alcohol abuse was admitted to the Nephrology Department because acute kidney injury. Previous medical unremarkable. Physical examination revealed severe dehydration and large (15 × 25 cm) verrucous mass (Figure 1A ) an associated ulceration localized in anal region. Small lesions were also on lower abdomen scrotum 1B). Testing for human immunodeficiency virus syphilis negative. Histopathology notable papillomatosis hyperkeratosis defining condyloma acuminata. The patient referred surgical treatment. Genital warts are caused by papillomavirus (HPV), more than 90% cases being related HPV 6 or 11 (Braga et al., 2012Braga J.C. Nadal S.R. Stiepcich M. de Souza Framil V.M. Muller H. Buschke-Loewenstein tumor: identification type 11.An Bras Dermatol. 2012; 87: 131-134Crossref PubMed Scopus (15) Google Scholar). Transmission occurs through direct contact infected skin mucous membranes (de Camargo 2014de C.C. Tasca K.I. Mendes M.B. Miot H.A. do Rosário L. Prevalence anogenital men HIV/AIDS factors.Open AIDS J. 2014; 8: 25-30Crossref (12) Giant Buschke–Löwenstein tumor is very rare, slow-growing, locally destructive variant carcinoma. It most commonly located glans penis, although it can be found vulva, vagina, rectum, bladder. Males affected often 70% occur individuals below age 50 (Fleischer 2001Fleischer Jr., A.B. Parrish C.A. Glenn R. Condylomata acuminata (genital warts): demographics treating physicians.Sex Transm Dis. 2001; 28: 643-647Crossref (70) treatment choice radical surgery since malignant transformation occur. consented image publication provided written consent.